Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SLC35D3 |
Gene ID: | 340146 |
Uniprot ID: | S35D3_HUMAN |
Immunogen Region: | 310-390 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 310-390 of human SLC35D3 (NP_001008783.1). |
Immunogen Sequence: | NYEDLEAQPRGEEAQLSGDQ LPFVMEELPGEGGNGRSEGG EAAGGPAQESRQEVRGSPRG VPLVAGSSEEGSRRSLKDAY L |
Function | Probable UDP-glucose transmembrane transporter involved in UDP-glucose transport from the cytosol to the lumen of synaptic vesicles. It is involved in platelet dense granules maturation. Alternatively, could function as a molecular adapter enhancing the formation of the PI3KC3-C1/AIC/autophagy initiation complex to promote autophagy in dopaminergic neurons. Could also regulate the plasma membrane localization of the D(1A) dopamine receptor/DRD1 and dopamine signaling. |
Protein Name | Solute Carrier Family 35 Member D3Fringe Connection-Like Protein 1 |
Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinEarly Endosome MembraneEndoplasmic Reticulum MembraneActive At Early Endosome Membrane In The Biosynthesis Of Mature Platelet-Dense Granules |
Alternative Antibody Names | Anti-Solute Carrier Family 35 Member D3 antibodyAnti-Fringe Connection-Like Protein 1 antibodyAnti-SLC35D3 antibodyAnti-FRCL1 antibody |
Information sourced from Uniprot.org