Anti-SLC35D3 antibody (310-390) (STJ119889)

SKU:
STJ119889
£112.50 - £524.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC35D3
Gene ID: 340146
Uniprot ID: S35D3_HUMAN
Immunogen Region: 310-390
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 310-390 of human SLC35D3 (NP_001008783.1).
Immunogen Sequence: NYEDLEAQPRGEEAQLSGDQ LPFVMEELPGEGGNGRSEGG EAAGGPAQESRQEVRGSPRG VPLVAGSSEEGSRRSLKDAY L
Function Probable UDP-glucose transmembrane transporter involved in UDP-glucose transport from the cytosol to the lumen of synaptic vesicles. It is involved in platelet dense granules maturation. Alternatively, could function as a molecular adapter enhancing the formation of the PI3KC3-C1/AIC/autophagy initiation complex to promote autophagy in dopaminergic neurons. Could also regulate the plasma membrane localization of the D(1A) dopamine receptor/DRD1 and dopamine signaling.
Protein Name Solute Carrier Family 35 Member D3
Fringe Connection-Like Protein 1
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Multi-Pass Membrane Protein
Early Endosome Membrane
Endoplasmic Reticulum Membrane
Active At Early Endosome Membrane In The Biosynthesis Of Mature Platelet-Dense Granules
Alternative Antibody Names Anti-Solute Carrier Family 35 Member D3 antibody
Anti-Fringe Connection-Like Protein 1 antibody
Anti-SLC35D3 antibody
Anti-FRCL1 antibody

Information sourced from Uniprot.org