| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC35D3 (310-390) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC35D3 |
| Gene ID: |
340146 |
| Uniprot ID: |
S35D3_HUMAN |
| Immunogen Region: |
310-390 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 310-390 of human SLC35D3 (NP_001008783.1). |
| Immunogen Sequence: |
NYEDLEAQPRGEEAQLSGDQ LPFVMEELPGEGGNGRSEGG EAAGGPAQESRQEVRGSPRG VPLVAGSSEEGSRRSLKDAY L |
| Function | Probable UDP-glucose transmembrane transporter involved in UDP-glucose transport from the cytosol to the lumen of synaptic vesicles. It is involved in platelet dense granules maturation. Alternatively, could function as a molecular adapter enhancing the formation of the PI3KC3-C1/AIC/autophagy initiation complex to promote autophagy in dopaminergic neurons. Could also regulate the plasma membrane localization of the D(1A) dopamine receptor/DRD1 and dopamine signaling. |
| Protein Name | Solute Carrier Family 35 Member D3Fringe Connection-Like Protein 1 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinEarly Endosome MembraneEndoplasmic Reticulum MembraneActive At Early Endosome Membrane In The Biosynthesis Of Mature Platelet-Dense Granules |
| Alternative Antibody Names | Anti-Solute Carrier Family 35 Member D3 antibodyAnti-Fringe Connection-Like Protein 1 antibodyAnti-SLC35D3 antibodyAnti-FRCL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
