| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC35A2 |
| Gene ID: | 7355 |
| Uniprot ID: | S35A2_HUMAN |
| Immunogen Region: | 1-242 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SLC35A2 (NP_001027460.1). |
| Immunogen Sequence: | MAAVGAGGSTAAPGPGAVSA GALEPGTASAAHRRLKYISL AVLVVQNASLILSIRYARTL PGDRFFATTAVVMAEVLKGL TCLLLLFAQKRGNVKHLVLF LHEAVLVQYVDTLKLAVPSL IYTLQNNLQYVAISNLPAAT FQPSPRCSQSHSLCLCLRLR ALRSPAASRAATTTAAVFPP WRPHHGALSAKVSAGEVRAG SNGGTQGRGTGVEGVGHLQD PSRHPPGPGSSGFGRWSFL |
| Function | Transports uridine diphosphate galactose (UDP-galactose) from the cytosol into the Golgi apparatus, functioning as an antiporter that exchanges UDP-galactose for UMP. It is also able to exchange UDP-galactose for AMP and CMP, and to transport UDP-N-acetylgalactosamine (UDP-GalNAc) and other nucleotide sugars. As a provider of UDP-galactose to galactosyltransferases present in the Golgi apparatus, it is necessary for globotriaosylceramide/globoside (Gb3Cer) synthesis from lactosylceramide. |
| Protein Name | Udp-Galactose TranslocatorSolute Carrier Family 35 Member A2Udp-Galactose TransporterUdp-Gal-TrUgt |
| Database Links | Reactome: R-HSA-5619072Reactome: R-HSA-727802 |
| Cellular Localisation | Isoform 1: Endoplasmic Reticulum MembraneGolgi Apparatus MembraneMulti-Pass Membrane ProteinIsoform 2: Golgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Udp-Galactose Translocator antibodyAnti-Solute Carrier Family 35 Member A2 antibodyAnti-Udp-Galactose Transporter antibodyAnti-Udp-Gal-Tr antibodyAnti-Ugt antibodyAnti-SLC35A2 antibodyAnti-UGALT antibodyAnti-UGT antibodyAnti-UGTL antibody |
Information sourced from Uniprot.org