| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC2A8 (200-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC2A8 |
| Gene ID: |
29988 |
| Uniprot ID: |
SL2A8_HUMAN |
| Immunogen Region: |
200-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-260 of human SLC2A8 (NP_055395.2). |
| Immunogen Sequence: |
CFMPETPRFLLTQHRRQEAM AALRFLWGSEQGWEDPPIGA EQSFHLALLRQPGIYKPFII G |
| Tissue Specificity | Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues. |
| Function | Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8Glucose Transporter Type 8Glut-8Glucose Transporter Type X1 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembranePrincipally IntracellularMay Move Between Intracellular Vesicles And The Plasma MembraneThe Dileucine Internalization Motif Is Critical For Intracellular Sequestration |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 antibodyAnti-Glucose Transporter Type 8 antibodyAnti-Glut-8 antibodyAnti-Glucose Transporter Type X1 antibodyAnti-SLC2A8 antibodyAnti-GLUT8 antibodyAnti-GLUTX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
