| Tissue Specificity | Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus. |
| Function | Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane. Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation such as the heart. |
| Protein Name | Long-Chain Fatty Acid Transport Protein 6Fatp-6Fatty Acid Transport Protein 6Arachidonate--Coa LigaseFatty-Acid-Coenzyme A Ligase - Very Long-Chain 2Long-Chain-Fatty-Acid--Coa LigaseSolute Carrier Family 27 Member 6Very Long-Chain Acyl-Coa Synthetase Homolog 1Vlcsh1Hvlcs-H1 |
| Database Links | Reactome: R-HSA-804914 |
| Cellular Localisation | Cell MembraneSarcolemmaMulti-Pass Membrane ProteinIn Heart Is Exclusively Located On The Sarcolemma In Areas Juxtaposed With Small Blood Vessels Where It Colocalizes Cd36 |
| Alternative Antibody Names | Anti-Long-Chain Fatty Acid Transport Protein 6 antibodyAnti-Fatp-6 antibodyAnti-Fatty Acid Transport Protein 6 antibodyAnti-Arachidonate--Coa Ligase antibodyAnti-Fatty-Acid-Coenzyme A Ligase - Very Long-Chain 2 antibodyAnti-Long-Chain-Fatty-Acid--Coa Ligase antibodyAnti-Solute Carrier Family 27 Member 6 antibodyAnti-Very Long-Chain Acyl-Coa Synthetase Homolog 1 antibodyAnti-Vlcsh1 antibodyAnti-Hvlcs-H1 antibodyAnti-SLC27A6 antibodyAnti-ACSVL2 antibodyAnti-FACVL2 antibodyAnti-FATP6 antibody |
Information sourced from Uniprot.org
