Anti-SLC15A2 antibody (STJA0004436)

SKU:
STJA0004436

Current Stock:
Host: Rabbit
Applications: IHC/ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Solute Carrier Family 15 Member 2 is suitable for use in Immunohistochemistry and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Concentration: 0.7 mg/mL
Dilution Range: IHC 1:50-1:200
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: SLC15A2
Gene ID: 6565
Uniprot ID: S15A2_HUMAN
Immunogen: Synthetic peptide of human SLC15A2
Tissue Specificity Expressed in kidney. Not detected in intestine. Highly expressed in macrophages.
Function Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and anionic dipeptides with a proton to peptide stoichiometry of 2:1 or 3:1. In kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate. Can also transport beta-lactam antibiotics, such as the aminocephalosporin cefadroxil, and other antiviral and anticancer drugs. Transports the dipeptide-like aminopeptidase inhibitor bestatin. Also able to transport carnosine. Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs). Mediates transport of bacterial peptidoglycans across the plasma membrane or, in macrophages, the phagosome membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand.
Protein Name Solute Carrier Family 15 Member 2
Kidney H(+/Peptide Cotransporter
Oligopeptide Transporter - Kidney Isoform
Peptide Transporter 2
Database Links Reactome: R-HSA-427975
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Phagosome Membrane
Cell Membrane
Associated With The Cell Membrane In Resting Macrophages And Enriched In Phagocytic Cups And Phagosomes After Particle Internalization
Alternative Antibody Names Anti-Solute Carrier Family 15 Member 2 antibody
Anti-Kidney H(+/Peptide Cotransporter antibody
Anti-Oligopeptide Transporter - Kidney Isoform antibody
Anti-Peptide Transporter 2 antibody
Anti-SLC15A2 antibody
Anti-PEPT2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance