Anti-SINHCAF antibody (1-100 aa) (STJ11106643)

SKU:
STJ11106643
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: SINHCAF
Gene ID: 58516
Uniprot ID: SHCAF_HUMAN
Immunogen Region: 1-100 aa
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SINHCAF (NP_001129283.1).
Immunogen Sequence: MFGFHKPKMYRSIEGCCICR AKSSSSRFTDSKRYEKDFQS CFGLHETRSGDICNACVLLV KRWKKLPAGSKKNWNHVVDA RAGPSLKTTLKPKKVKTLSG
Function Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway. Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming.
Protein Name Sin3-Hdac Complex-Associated Factor
Protein Fam60a
Tera Protein Homolog
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Sin3-Hdac Complex-Associated Factor antibody
Anti-Protein Fam60a antibody
Anti-Tera Protein Homolog antibody
Anti-SINHCAF antibody
Anti-C12orf14 antibody
Anti-FAM60A antibody
Anti-L4 antibody

Information sourced from Uniprot.org

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