| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERTAD1 |
| Gene ID: | 29950 |
| Uniprot ID: | SRTD1_HUMAN |
| Immunogen Region: | 1-236 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2). |
| Immunogen Sequence: | MLSKGLKRKREEEEEKEPLA VDSWWLDPGHTAVAQAPPAV ASSSLFDLSVLKLHHSLQQS EPDLRHLVLVVNTLRRIQAS MAPAAALPPVPSPPAAPSVA DNLLASSDAALSASMASLLE DLSHIEGLSQAPQPLADEGP PGRSIGGAAPSLGALDLLGP ATGCLLDDGLEGLFEDIDTS MYDNELWAPASEGLKPGPED GPGKEEAPELDEAELDYLMD VLVGTQALERPPGPGR |
| Post Translational Modifications | Polyubiquitinated, which promotes proteasomal degradation. |
| Function | Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A. |
| Protein Name | Serta Domain-Containing Protein 1Cdk4-Binding Protein P34sei1Sei-1P34(Sei-1Transcriptional Regulator Interacting With The Phd-Bromodomain 1Trip-Br1 |
| Alternative Antibody Names | Anti-Serta Domain-Containing Protein 1 antibodyAnti-Cdk4-Binding Protein P34sei1 antibodyAnti-Sei-1 antibodyAnti-P34(Sei-1 antibodyAnti-Transcriptional Regulator Interacting With The Phd-Bromodomain 1 antibodyAnti-Trip-Br1 antibodyAnti-SERTAD1 antibodyAnti-SEI1 antibodyAnti-TRIPBR1 antibody |
Information sourced from Uniprot.org