| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SCARF1/SREC (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 85-90kDa band observed in Human Heart lysates (calculated MW of 87.4kDa according to NP_003684.2). Recommended concentration: 0.3-1.0µg/ml. Primary incubation was 1 hour. An add |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SCARF1 |
| Gene ID: | 8578 |
| Uniprot ID: | SREC_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_003684.2; NP_663325.1; NP_663327.2 |
| Specificity: | This antibody is expected to recognise all three reported isoforms (NP_003684.2; NP_663325.1; NP_663327.2). Epitope corresponding to aa 20-31, mapping to the mature human SCARF1/SREC1 protein. |
| Immunogen Sequence: | SELDPKGQHVC |
| Function | Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth. |
| Protein Name | Scavenger Receptor Class F Member 1Acetyl Ldl ReceptorScavenger Receptor Expressed By Endothelial Cells 1Srec-I |
| Database Links | Reactome: R-HSA-3000484 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Scavenger Receptor Class F Member 1 antibodyAnti-Acetyl Ldl Receptor antibodyAnti-Scavenger Receptor Expressed By Endothelial Cells 1 antibodyAnti-Srec-I antibodyAnti-SCARF1 antibodyAnti-KIAA0149 antibodyAnti-SREC antibody |
Information sourced from Uniprot.org