| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RXFP1 |
| Gene ID: | 59350 |
| Uniprot ID: | RXFP1_HUMAN |
| Immunogen Region: | 673-757 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 673-757 of human RXFP1 (NP_067647.2). |
| Immunogen Sequence: | NSALNPILYTLTTRPFKEMI HRFWYNYRQRKSMDSKGQKT YAPSFIWVEMWPLQEMPPEL MKPDLFTYPCEMSLISQSTR LNSYS |
| Tissue Specificity | Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen. |
| Function | Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. |
| Protein Name | Relaxin Receptor 1Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7Relaxin Family Peptide Receptor 1 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-444821 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Relaxin Receptor 1 antibodyAnti-Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7 antibodyAnti-Relaxin Family Peptide Receptor 1 antibodyAnti-RXFP1 antibodyAnti-LGR7 antibody |
Information sourced from Uniprot.org