| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RXFP1 (673-757) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RXFP1 |
| Gene ID: |
59350 |
| Uniprot ID: |
RXFP1_HUMAN |
| Immunogen Region: |
673-757 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 673-757 of human RXFP1 (NP_067647.2). |
| Immunogen Sequence: |
NSALNPILYTLTTRPFKEMI HRFWYNYRQRKSMDSKGQKT YAPSFIWVEMWPLQEMPPEL MKPDLFTYPCEMSLISQSTR LNSYS |
| Tissue Specificity | Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen. |
| Function | Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. |
| Protein Name | Relaxin Receptor 1Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7Relaxin Family Peptide Receptor 1 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-444821 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Relaxin Receptor 1 antibodyAnti-Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7 antibodyAnti-Relaxin Family Peptide Receptor 1 antibodyAnti-RXFP1 antibodyAnti-LGR7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
