| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein CBFA2T1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RUNX1T1 |
| Gene ID: |
862 |
| Uniprot ID: |
MTG8_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RUNX1T1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human RUNX1T1 |
| Function | Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12. Acts as a negative regulator of adipogenesis. The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal. |
| Protein Name | Protein Cbfa2t1Cyclin-D-Related ProteinEight Twenty One ProteinProtein EtoProtein Mtg8Zinc Finger Mynd Domain-Containing Protein 2 |
| Cellular Localisation | NucleusColocalizes With Atn1 In Discrete Nuclear Dots |
| Alternative Antibody Names | Anti-Protein Cbfa2t1 antibodyAnti-Cyclin-D-Related Protein antibodyAnti-Eight Twenty One Protein antibodyAnti-Protein Eto antibodyAnti-Protein Mtg8 antibodyAnti-Zinc Finger Mynd Domain-Containing Protein 2 antibodyAnti-RUNX1T1 antibodyAnti-AML1T1 antibodyAnti-CBFA2T1 antibodyAnti-CDR antibodyAnti-ETO antibodyAnti-MTG8 antibodyAnti-ZMYND2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
