| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPLANE2 |
| Gene ID: | 79363 |
| Uniprot ID: | CPLN2_HUMAN |
| Immunogen Region: | 1-220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RSG1 (NP_112169.2). |
| Immunogen Sequence: | MARPPVPGSVVVPNWHESAE GKEYLACILRKNRRRVFGLL ERPVLLPPVSIDTASYKIFV SGKSGVGKTALVAKLAGLEV PVVHHETTGIQTTVVFWPAK LQASSRVVMFRFEFWDCGES ALKKFDHMLLACMENTDAFL FLFSFTDRASFEDLPGQLAR IAGEAPGVVRMVIGSKFDQY MHTDVPERDLTAFRQAWELP LLRVKSVPGRRLADGRTLDG |
| Function | Required for efficient primary cilia initiation, regulating a late step in cilia initiation. Plays a role in the final maturation of the mother centriole and ciliary vesicle that allows extension of the ciliary axoneme. |
| Protein Name | Ciliogenesis And Planar Polarity Effector 2Rem2- And Rab-Like Small Gtpase 1 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleLocalizes At The Transition ZoneA Region Between The Basal Body And The Ciliary AxonemeRecruitment To The Centriole Depends On Ttbk2IntuAnd Its Own Gtpase Activity |
| Alternative Antibody Names | Anti-Ciliogenesis And Planar Polarity Effector 2 antibodyAnti-Rem2- And Rab-Like Small Gtpase 1 antibodyAnti-CPLANE2 antibodyAnti-C1orf89 antibodyAnti-RSG1 antibody |
Information sourced from Uniprot.org