| Tissue Specificity | Expressed in all tissues tested. |
| Function | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. |
| Protein Name | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 2Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 Kda SubunitRibiirRibophorin IiRpn-IiRibophorin-2 |
| Database Links | Reactome: R-HSA-1799339Reactome: R-HSA-446203Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic ReticulumEndoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 2 antibodyAnti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 Kda Subunit antibodyAnti-Ribiir antibodyAnti-Ribophorin Ii antibodyAnti-Rpn-Ii antibodyAnti-Ribophorin-2 antibodyAnti-RPN2 antibody |
Information sourced from Uniprot.org
