| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RASSF2 (70-160) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RASSF2 |
| Gene ID: |
9770 |
| Uniprot ID: |
RASF2_HUMAN |
| Immunogen Region: |
70-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human RASSF2 (NP_055552.1). |
| Immunogen Sequence: |
MQDDNERIRPPPSSSSWHSG CNLGAQGTTLKPLTVPKVQI SEVDAPPEGDQMPSSTDSRG LKPLQEDTPQLMRTRSDVGV RRRGNVRTPSD |
| Tissue Specificity | Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. |
| Post Translational Modifications | Phosphorylated by STK3/MST2 and STK4/MST1. |
| Function | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. |
| Protein Name | Ras Association Domain-Containing Protein 2 |
| Cellular Localisation | NucleusCytoplasmChromosomeCentromereKinetochoreTranslocates To The Cytoplasm In The Presence Of Stk3/Mst2 And Stk4/Mst1 |
| Alternative Antibody Names | Anti-Ras Association Domain-Containing Protein 2 antibodyAnti-RASSF2 antibodyAnti-CENP-34 antibodyAnti-KIAA0168 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
