| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ras association domain-containing protein 2 (109-158 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RASSF2 |
| Gene ID: | 9770 |
| Uniprot ID: | RASF2_HUMAN |
| Immunogen Region: | 109-158 aa |
| Specificity: | RASSF2 Polyclonal Antibody detects endogenous levels of RASSF2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RASSF2 at the amino acid range 109-158 |
| Post Translational Modifications | Phosphorylated by STK3/MST2 and STK4/MST1. |
| Function | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. |
| Protein Name | Ras Association Domain-Containing Protein 2 |
| Cellular Localisation | NucleusCytoplasmChromosomeCentromereKinetochoreTranslocates To The Cytoplasm In The Presence Of Stk3/Mst2 And Stk4/Mst1 |
| Alternative Antibody Names | Anti-Ras Association Domain-Containing Protein 2 antibodyAnti-RASSF2 antibodyAnti-CENP-34 antibodyAnti-KIAA0168 antibody |
Information sourced from Uniprot.org