Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RASEF (200-500) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RASEF |
Gene ID: |
158158 |
Uniprot ID: |
RASEF_HUMAN |
Immunogen Region: |
200-500 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human RASEF (NP_689786.2). |
Immunogen Sequence: |
MQLSELEEEMDQRIQAAEHK TRKDEKRKAEEALSDLRRQY ETEVGDLQVTIKKLRKLEEQ SKRVSQKEDVAALKKQIYDL SMENQKVKKDLLEAQTNIAF LQSELDALKSDYADQSLNTE RDLEIIRAYTEDRNSLERQI EILQTANRKLHDSNDGLRSA LENSYSKFNRSLHINNISPG NTISRSSPKFIGHSPQPLGY DRSSRSSYVDEDCDSLALCD PLQRTNCEVDSLPESCFDS |
Tissue Specificity | Down-regulated in cutaneous melanoma cells but not in breast cancer cells. |
Function | Binds predominantly GDP, and also GTP. Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules. |
Protein Name | Ras And Ef-Hand Domain-Containing ProteinRas-Related Protein Rab-45 |
Cellular Localisation | CytoplasmPerinuclear Region |
Alternative Antibody Names | Anti-Ras And Ef-Hand Domain-Containing Protein antibodyAnti-Ras-Related Protein Rab-45 antibodyAnti-RASEF antibodyAnti-RAB45 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance