| Tissue Specificity | Broadly expressed, with highest levels in skeletal muscle. |
| Function | May act as an adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function. |
| Protein Name | Ran-Binding Protein 10Ranbp10 |
| Database Links | Reactome: R-HSA-8851805 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Ran-Binding Protein 10 antibodyAnti-Ranbp10 antibodyAnti-RANBP10 antibodyAnti-KIAA1464 antibody |
Information sourced from Uniprot.org
