||Human, Mouse, Rat
||Rabbit polyclonal anti-RAB3GAP1 antibody is suitable for use in Western Blot.
||FOR RESEARCH USE ONLY (RUO).
||PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
||Store at-20°C. Avoid freeze/thaw cycles.
| Tissue Specificity || Ubiquitous. |
| Function || Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters. |
| Protein Name || Rab3 Gtpase-Activating Protein Catalytic SubunitRab3 Gtpase-Activating Protein 130 Kda SubunitRab3-Gap P130Rab3-Gap |
| Database Links || Reactome: R-HSA-6811436Reactome: R-HSA-8876198 |
| Cellular Localisation || CytoplasmIn NeuronsIt Is Enriched In The Synaptic Soluble Fraction |
| Alternative Antibody Names || Anti-Rab3 Gtpase-Activating Protein Catalytic Subunit antibodyAnti-Rab3 Gtpase-Activating Protein 130 Kda Subunit antibodyAnti-Rab3-Gap P130 antibodyAnti-Rab3-Gap antibodyAnti-RAB3GAP1 antibodyAnti-KIAA0066 antibodyAnti-RAB3GAP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance