| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RAB11FIP4 (338-637) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAB11FIP4 |
| Gene ID: |
84440 |
| Uniprot ID: |
RFIP4_HUMAN |
| Immunogen Region: |
338-637 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 338-637 of human RAB11FIP4 (NP_116321.2). |
| Immunogen Sequence: |
NDITEKVSFLEKKVTELEND SLTNGDLKSKLKQENTQLVH RVHELEEMVKDQETTAEQAL EEEARRHREAYGKLEREKAT EVELLNARVQQLEEENTELR TTVTRLKSQTEKLDEERQRM SDRLEDTSLRLKDEMDLYKR MMDKLRQNRLEFQKEREATQ ELIEDLRKELEHLQMYKLDC ERPGRGRSASSGLGEFNARA REVELEHEVKRLKQENYKLR DQNDDLNGQILSLSLYEAK |
| Tissue Specificity | Present at high level in testis (at protein level). Weakly expressed in other tissues. |
| Function | Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus.this function is independent of ARF6. |
| Protein Name | Rab11 Family-Interacting Protein 4Fip4-Rab11Rab11-Fip4Arfophilin-2 |
| Cellular Localisation | EndosomeCytoplasmCytoskeletonSpindleMicrotubule Organizing CenterCentrosomeRecycling Endosome MembranePeripheral Membrane ProteinCleavage FurrowMidbodyCytoplasmic VesicleRecruited To The Cleavage Furrow And The Midbody During Cytokinesis |
| Alternative Antibody Names | Anti-Rab11 Family-Interacting Protein 4 antibodyAnti-Fip4-Rab11 antibodyAnti-Rab11-Fip4 antibodyAnti-Arfophilin-2 antibodyAnti-RAB11FIP4 antibodyAnti-ARFO2 antibodyAnti-KIAA1821 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
