| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTPN18 |
| Gene ID: | 26469 |
| Uniprot ID: | PTN18_HUMAN |
| Immunogen Region: | 1-210 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PTPN18 (NP_001135842.1). |
| Immunogen Sequence: | MSRSLDSARSFLERLEARGG REGAVLAGEFSKRCERYWAQ EQEPLQTGLFCITLIKEKWL NEDIMLRTLKVTFQKESRSV YQLQYMSWPDRGVPSSPDHM LAMVEEARRLQGSGPEPLCV HCSAGCGRTGVLCTVDYVRQ LLLTQMIPPDFSLFDVVLKM RKQRPAAVQTEEQYRFLYHT VAQMFCSTLQNASPHYQNIK ENCAPLYDDA |
| Tissue Specificity | Expressed in brain, colon and several tumor-derived cell lines. |
| Function | Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. |
| Protein Name | Tyrosine-Protein Phosphatase Non-Receptor Type 18Brain-Derived Phosphatase |
| Database Links | Reactome: R-HSA-8863795Reactome: R-HSA-9008059 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Tyrosine-Protein Phosphatase Non-Receptor Type 18 antibodyAnti-Brain-Derived Phosphatase antibodyAnti-PTPN18 antibodyAnti-BDP1 antibody |
Information sourced from Uniprot.org