| Tissue Specificity | Expressed in all tissues and cell lines tested with the highest level of abundance in testis. |
| Post Translational Modifications | Autophosphorylated on serine residues. Myristoylated. Required for membrane association. Prerequisite for palmitoylation to occur. Palmitoylated. |
| Function | May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. |
| Protein Name | Serine/Threonine-Protein Kinase H1Protein Serine Kinase H1Psk-H1 |
| Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleus SpeckleEndoplasmic Reticulum MembraneLipid-AnchorCell MembraneLocalized In The Brefeldin A-Sensitive Golgi CompartmentAt CentrosomesIn The Nucleus With A Somewhat Speckle-Like PresenceMembrane-Associated To The Endoplasmic Reticulum (Er) And The Plasma Membrane (Pm)And More Diffusely In The CytoplasmFound To Concentrate In Splicing Factor Compartments (Sfcs) Within The Nucleus Of Interphase CellsThe Acylation-Negative Form May Be Only Cytoplasmic And NuclearAcylation Seems To Allow The Sequestering To The Intracellular MembranesMyristoylation May Mediate Targeting To The Intracellular Non-Golgi Membranes And Palmitoylation May Mediate The Targeting To The Golgi MembranesDual Acylation Is Required To Stabilize The Interaction With Golgi Membranes |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase H1 antibodyAnti-Protein Serine Kinase H1 antibodyAnti-Psk-H1 antibodyAnti-PSKH1 antibody |
Information sourced from Uniprot.org
