| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPT2 |
| Gene ID: | 9374 |
| Uniprot ID: | PPT2_HUMAN |
| Immunogen Region: | 28-302 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-302 of human PPT2 (NP_005146.4). |
| Immunogen Sequence: | APAPHRASYKPVIVVHGLFD SSYSFRHLLEYINETHPGTV VTVLDLFDGRESLRPLWEQV QGFREAVVPIMAKAPQGVHL ICYSQGGLVCRALLSVMDDH NVDSFISLSSPQMGQYGDTD YLKWLFPTSMRSNLYRICYS PWGQEFSICNYWHDPHHDDL YLNASSFLALINGERDHPNA TVWRKNFLRVGHLVLIGGPD DGVITPWQSSFFGFYDANET VLEMEEQLVYLRDSFGLKT |
| Tissue Specificity | Broadly expressed, with highest levels in skeletal muscle. |
| Function | Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins. |
| Protein Name | Lysosomal Thioesterase Ppt2Ppt-2S-Thioesterase G14 |
| Database Links | Reactome: R-HSA-75105 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Lysosomal Thioesterase Ppt2 antibodyAnti-Ppt-2 antibodyAnti-S-Thioesterase G14 antibodyAnti-PPT2 antibody |
Information sourced from Uniprot.org