| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PPP6R3 (1-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PPP6R3 |
| Gene ID: |
55291 |
| Uniprot ID: |
PP6R3_HUMAN |
| Immunogen Region: |
1-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PPP6R3 (NP_060782.2). |
| Immunogen Sequence: |
MFWKFDLHSSSHIDTLLERE DVTLKELMDEEDVLQECKAQ NRKLIEFLLKAECLEDLVSF IIEEPPQDMDEKIRYKYPNI SCELLTSDVSQMNDRLGEDE SLLMKLYSFLLNDSPLNPLL ASFFSKVLSILISRKPEQIV DFLKKKHDFVDLIIKHIGTS AIMDLLLRLLTCIEPPQPRQ DVLNWLNEEKIIQRLVEIVH PSQEEDRHSNASQSLCEIVR LSRDQMLQIQNSTEPDPLL |
| Tissue Specificity | Expressed in skeletal muscle, placenta, heart, pancreas, testis, brain, lung, liver, kidney, spleen, thymus, prostate, small intestine, colon and leukocytes. |
| Function | Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance. |
| Protein Name | Serine/Threonine-Protein Phosphatase 6 Regulatory Subunit 3Saps Domain Family Member 3Sporulation-Induced Transcript 4-Associated Protein Sapl |
| Database Links | Reactome: R-HSA-171319Reactome: R-HSA-204005 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 6 Regulatory Subunit 3 antibodyAnti-Saps Domain Family Member 3 antibodyAnti-Sporulation-Induced Transcript 4-Associated Protein Sapl antibodyAnti-PPP6R3 antibodyAnti-C11orf23 antibodyAnti-KIAA1558 antibodyAnti-PP6R3 antibodyAnti-SAPL antibodyAnti-SAPS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and APEH knockout (KO) 293T cells, using [KO Validated] APEH Rabbit polyclonal antibody (STJ11100788) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89724/358205/STJ11100788_1__51624.1713122526.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and APEH knockout (KO) 293T cells, using [KO Validated] APEH Rabbit polyclonal antibody (STJ11100788) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")