| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPCS |
| Gene ID: | 79717 |
| Uniprot ID: | PPCS_HUMAN |
| Immunogen Region: | 1-311 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-311 of human PPCS (NP_078940.2). |
| Immunogen Sequence: | MAEMDPVAEFPQPPGAARWA EVMARFAARLGAQGRRVVLV TSGGTKVPLEARPVRFLDNF SSGRRGATSAEAFLAAGYGV LFLYRARSAFPYAHRFPPQT WLSALRPSGPALSGLLSLEA EENALPGFAEALRSYQEAAA AGTFLAVEFTTLADYLHLLQ AAAQALNPLGPSAMFYLAAA VSDFYVPVSEMPEHKIQSSG GPLQITMKMVPKLLSPLVKD WAPKAFIISFKLETDPAIV |
| Function | Catalyzes the second step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. Has a preference for ATP over CTP as a cosubstrate. |
| Protein Name | Phosphopantothenate--Cysteine LigasePhosphopantothenoylcysteine SynthetasePpc Synthetase |
| Database Links | Reactome: R-HSA-196783 |
| Alternative Antibody Names | Anti-Phosphopantothenate--Cysteine Ligase antibodyAnti-Phosphopantothenoylcysteine Synthetase antibodyAnti-Ppc Synthetase antibodyAnti-PPCS antibodyAnti-COAB antibody |
Information sourced from Uniprot.org