| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POU4F3 |
| Gene ID: | 5459 |
| Uniprot ID: | PO4F3_HUMAN |
| Immunogen Region: | 1-180 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU4F3 (NP_002691.1). |
| Immunogen Sequence: | MMAMNSKQPFGMHPVLQEPK FSSLHSGSEAMRRVCLPAPQ LQGNIFGSFDESLLARAEAL AAVDIVSHGKNHPFKPDATY HTMSSVPCTSTSSTVPISHP AALTSHPHHAVHQGLEGDLL EHISPTLSVSGLGAPEHSVM PAQIHPHHLGAMGHLHQAMG MSHPHTVAPHSAMPACLSDV |
| Tissue Specificity | Brain. Seems to be specific to the retina. |
| Function | Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear. |
| Protein Name | Pou Domain - Class 4 - Transcription Factor 3Brain-Specific Homeobox/Pou Domain Protein 3cBrain-3cBrn-3c |
| Cellular Localisation | NucleusCytoplasmPreferentially Localized In The Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 4 - Transcription Factor 3 antibodyAnti-Brain-Specific Homeobox/Pou Domain Protein 3c antibodyAnti-Brain-3c antibodyAnti-Brn-3c antibodyAnti-POU4F3 antibodyAnti-BRN3C antibody |
Information sourced from Uniprot.org