| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PMF1 (1-205) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PMF1 |
| Gene ID: |
100527963/11243 |
| Uniprot ID: |
PMF1_HUMAN |
| Immunogen Region: |
1-205 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human PMF1 (NP_009152.2). |
| Immunogen Sequence: |
MAEASSANLGSGCEEKRHEG SSSESVPPGTTISRVKLLDT MVDTFLQKLVAAGSYQRFTD CYKCFYQLQPAMTQQIYDKF IAQLQTSIREEISDIKEEGN LEAVLNALDKIVEEGKVRKE PAWRPSGIPEKDLHSVMAPY FLQQRDTLRRHVQKQEAENQ QLADAVLAGRRQVEELQLQV QAQQQAWQALHREQRELVAV LREPE |
| Tissue Specificity | Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver. |
| Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. |
| Protein Name | Polyamine-Modulated Factor 1Pmf-1 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusChromosomeCentromereKinetochoreAssociated With The Kinetochore |
| Alternative Antibody Names | Anti-Polyamine-Modulated Factor 1 antibodyAnti-Pmf-1 antibodyAnti-PMF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
