| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLSCR4 |
| Gene ID: | 57088 |
| Uniprot ID: | PLS4_HUMAN |
| Immunogen Region: | 1-270 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PLSCR4 (NP_065086.2). |
| Immunogen Sequence: | MSGVVPTAPEQPAGEMENQT KPPDPRPDAPPEYNSHFLPG PPGTAVPPPTGYPGGLPMGY YSPQQPSTFPLYQPVGGIHP VRYQPGKYPMPNQSVPITWM PGPTPMANCPPGLEYLVQLD NIHVLQHFEPLEMMTCFETN NRYDIKNNSDQMVYIVTEDT DDFTRNAYRTLRPFVLRVTD CMGREIMTMQRPFRCTCCCF CCPSARQELEVQCPPGVTIG FVAEHWNLCRAVYSIQNEK |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes. |
| Function | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. |
| Protein Name | Phospholipid Scramblase 4Pl Scramblase 4Ca(2+-Dependent Phospholipid Scramblase 4Cell Growth-Inhibiting Gene 43 ProteinTra1 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Phospholipid Scramblase 4 antibodyAnti-Pl Scramblase 4 antibodyAnti-Ca(2+-Dependent Phospholipid Scramblase 4 antibodyAnti-Cell Growth-Inhibiting Gene 43 Protein antibodyAnti-Tra1 antibodyAnti-PLSCR4 antibodyAnti-GIG43 antibody |
Information sourced from Uniprot.org