| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PLSCR4 (1-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLSCR4 |
| Gene ID: |
57088 |
| Uniprot ID: |
PLS4_HUMAN |
| Immunogen Region: |
1-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PLSCR4 (NP_065086.2). |
| Immunogen Sequence: |
MSGVVPTAPEQPAGEMENQT KPPDPRPDAPPEYNSHFLPG PPGTAVPPPTGYPGGLPMGY YSPQQPSTFPLYQPVGGIHP VRYQPGKYPMPNQSVPITWM PGPTPMANCPPGLEYLVQLD NIHVLQHFEPLEMMTCFETN NRYDIKNNSDQMVYIVTEDT DDFTRNAYRTLRPFVLRVTD CMGREIMTMQRPFRCTCCCF CCPSARQELEVQCPPGVTIG FVAEHWNLCRAVYSIQNEK |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes. |
| Function | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. |
| Protein Name | Phospholipid Scramblase 4Pl Scramblase 4Ca(2+-Dependent Phospholipid Scramblase 4Cell Growth-Inhibiting Gene 43 ProteinTra1 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Phospholipid Scramblase 4 antibodyAnti-Pl Scramblase 4 antibodyAnti-Ca(2+-Dependent Phospholipid Scramblase 4 antibodyAnti-Cell Growth-Inhibiting Gene 43 Protein antibodyAnti-Tra1 antibodyAnti-PLSCR4 antibodyAnti-GIG43 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
