| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLRG1 |
| Gene ID: | 5356 |
| Uniprot ID: | PLRG1_HUMAN |
| Immunogen Region: | 1-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PLRG1 (NP_001188493.1). |
| Immunogen Sequence: | MVEEVQKHSVHTLVFRSLKR THDMFVADNGKPVPLDEESH KRKMAIKLRNEYGPVLHMPT SKENLKEKGPQNATDSYVHK QYPANQGQEVEYFVAGVALT ADTKIQRMPSESAAQSLAVA LPLQTKADANRTAPSGSEYR HPGASDRPQPTAMNSIVMET GNTKNSALMAKKAPTMPKPQ WHPPWKLYRV |
| Function | Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | Pleiotropic Regulator 1 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Pleiotropic Regulator 1 antibodyAnti-PLRG1 antibody |
Information sourced from Uniprot.org