| Host: |
Goat |
| Applications: |
Pep-ELISA/FC/IF |
| Reactivity: |
Human/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Goat polyclonal antibody anti-Plexin D1 (Internal) is suitable for use in ELISA, Flow Cytometry and Immunofluorescence research applications. |
| Clonality : |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:16000.IHC:.IF: Strong expression of the protein seen in the plasma membrane and cytoplasm of HeLa and U251cells. Recommended concentration: 10µg/ml. FC:Flow cytometric analysis of K562 ce |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
PLXND1 |
| Gene ID: |
23129 |
| Uniprot ID: |
PLXD1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_055918.2 |
| Immunogen Sequence: |
LAEPKKSHRQSH |
| Function | Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. |
| Protein Name | Plexin-D1 |
| Database Links | Reactome: R-HSA-416700Reactome: R-HSA-9013508Reactome: R-HSA-9696270 |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinCell ProjectionLamellipodium Membrane |
| Alternative Antibody Names | Anti-Plexin-D1 antibodyAnti-PLXND1 antibodyAnti-KIAA0620 antibody |
Information sourced from Uniprot.org
