| Tissue Specificity | Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells. |
| Function | May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis. |
| Protein Name | Pleckstrin Homology Domain-Containing Family F Member 2Ph Domain-Containing Family F Member 2Endoplasmic Reticulum-Associated Apoptosis-Involved Protein Containing Ph And Fyve DomainsEapfPh And Fyve Domain-Containing Protein 2Phafin-2Phafin2Zinc Finger Fyve Domain-Containing Protein 18 |
| Cellular Localisation | Early Endosome MembranePeripheral Membrane ProteinEndoplasmic ReticulumColocalizes With Eea1 And Rab5 At Endosomal Membrane Fusion Hot SpotsMay Translocate To The Endoplasmic Reticulum In The Early Phase Of Apoptosis |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family F Member 2 antibodyAnti-Ph Domain-Containing Family F Member 2 antibodyAnti-Endoplasmic Reticulum-Associated Apoptosis-Involved Protein Containing Ph And Fyve Domains antibodyAnti-Eapf antibodyAnti-Ph And Fyve Domain-Containing Protein 2 antibodyAnti-Phafin-2 antibodyAnti-Phafin2 antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 18 antibodyAnti-PLEKHF2 antibodyAnti-ZFYVE18 antibody |
Information sourced from Uniprot.org
