| Function | May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8. |
| Protein Name | Pleckstrin Homology Domain-Containing Family F Member 1Ph Domain-Containing Family F Member 1Lysosome-Associated Apoptosis-Inducing Protein Containing Ph And Fyve DomainsApoptosis-Inducing ProteinPh And Fyve Domain-Containing Protein 1Phafin-1Zinc Finger Fyve Domain-Containing Protein 15 |
| Cellular Localisation | NucleusCytoplasmPerinuclear RegionLysosomeTranslocates To Lysosome During Apoptosis |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family F Member 1 antibodyAnti-Ph Domain-Containing Family F Member 1 antibodyAnti-Lysosome-Associated Apoptosis-Inducing Protein Containing Ph And Fyve Domains antibodyAnti-Apoptosis-Inducing Protein antibodyAnti-Ph And Fyve Domain-Containing Protein 1 antibodyAnti-Phafin-1 antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 15 antibodyAnti-PLEKHF1 antibodyAnti-APPD antibodyAnti-LAPF antibodyAnti-ZFYVE15 antibody |
Information sourced from Uniprot.org
