| Function | Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. Can independently activate and synergize with PIT-1 on pituitary-specific target gene promoters, thus may subserve functions in generating both precursor and specific cell phenotypes in the anterior pituitary gland and in several other organs. Can activate pituitary transcription of the proopiomelanocortin gene. |
| Protein Name | Pituitary Homeobox 1Hindlimb-Expressed Homeobox Protein BackfootHomeobox Protein P-OtxHomeobox Protein Pitx1Paired-Like Homeodomain Transcription Factor 1Pituitary Otx-Related Factor |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pituitary Homeobox 1 antibodyAnti-Hindlimb-Expressed Homeobox Protein Backfoot antibodyAnti-Homeobox Protein P-Otx antibodyAnti-Homeobox Protein Pitx1 antibodyAnti-Paired-Like Homeodomain Transcription Factor 1 antibodyAnti-Pituitary Otx-Related Factor antibodyAnti-Pitx1 antibodyAnti-Bft antibodyAnti-Potx antibodyAnti-Ptx1 antibody |
Information sourced from Uniprot.org
