| Function | Pore-forming subunit of the mechanosensitive non-specific cation Piezo channel required for rapidly adapting mechanically activated (MA) currents and has a key role in sensing touch and tactile pain. Piezo channels are homotrimeric three-blade propeller-shaped structure that utilize a cap-motion and plug-and-latch mechanism to gate their ion-conducting pathways. In inner ear hair cells, PIEZO1/2 subunits may constitute part of the mechanotransducer (MET) non-selective cation channel complex where they may act as pore-forming ion-conducting component in the complex. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. |
| Protein Name | Piezo-Type Mechanosensitive Ion Channel Component 2Protein Fam38b |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Piezo-Type Mechanosensitive Ion Channel Component 2 antibodyAnti-Protein Fam38b antibodyAnti-PIEZO2 antibodyAnti-C18orf30 antibodyAnti-C18orf58 antibodyAnti-FAM38B antibody |
Information sourced from Uniprot.org
