| Tissue Specificity | Expressed in liver, kidney, brain cortex and eye lens (at protein level). |
| Function | Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels. |
| Protein Name | 4'-Phosphopantetheine PhosphataseInactive Pantothenic Acid Kinase 4Mpank4 |
| Database Links | Reactome: R-MMU-199220 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-4'-Phosphopantetheine Phosphatase antibodyAnti-Inactive Pantothenic Acid Kinase 4 antibodyAnti-Mpank4 antibodyAnti-Pank4 antibody |
Information sourced from Uniprot.org
