Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-PHKA2 (620-780) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:200-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PHKA2 |
Gene ID: |
5256 |
Uniprot ID: |
KPB2_HUMAN |
Immunogen Region: |
620-780 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 620-780 of human PHKA2 (NP_000283.1). |
Immunogen Sequence: |
DPDCDEKLFDNASEGTFSPD SDSDLVGYLEDTCNQESQDE LDHYINHLLQSTSLRSYLPP LCKNTEDRHVFSAIHSTRDI LSVMAKAKGLEVPFVPMTLP TKVLSAHRKSLNLVDSPQPL LEKVPESDFQWPRDDHGDVD CEKLVEQLKDCSNLQDQADI L |
Tissue Specificity | Predominantly expressed in liver and other non-muscle tissues. |
Post Translational Modifications | Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated. |
Function | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. |
Protein Name | Phosphorylase B Kinase Regulatory Subunit Alpha - Liver IsoformPhosphorylase Kinase Alpha L Subunit |
Database Links | Reactome: R-HSA-70221 |
Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
Alternative Antibody Names | Anti-Phosphorylase B Kinase Regulatory Subunit Alpha - Liver Isoform antibodyAnti-Phosphorylase Kinase Alpha L Subunit antibodyAnti-PHKA2 antibodyAnti-PHKLA antibodyAnti-PYK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance