| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PERP (C-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PERP |
| Gene ID: |
64065 |
| Uniprot ID: |
PERP_HUMAN |
| Immunogen Region: |
C-Term |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human PERP (NP_071404.2). |
| Immunogen Sequence: |
CGPQMLVFLRVIGGLLALAA VFQIISLVIYPVKYTQTFTL HANPAVTYIYNWAYGFGWAA TIILIGCAFFFCCLPNYEDD LLGNAKPRYFYTSA |
| Tissue Specificity | Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts. |
| Function | Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. |
| Protein Name | P53 Apoptosis Effector Related To Pmp-22Keratinocyte-Associated Protein 1Kcp-1P53-Induced Protein Pigpc1Transmembrane Protein Thw |
| Database Links | Reactome: R-HSA-6803205Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell JunctionDesmosomeCell MembraneMulti-Pass Membrane ProteinAssociated With DesmosomesColocalizes With Krt14 In The Cell Membrane |
| Alternative Antibody Names | Anti-P53 Apoptosis Effector Related To Pmp-22 antibodyAnti-Keratinocyte-Associated Protein 1 antibodyAnti-Kcp-1 antibodyAnti-P53-Induced Protein Pigpc1 antibodyAnti-Transmembrane Protein Thw antibodyAnti-PERP antibodyAnti-KCP1 antibodyAnti-KRTCAP1 antibodyAnti-PIGPC1 antibodyAnti-THW antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
