Host: | Rabbit |
Applications: | IHC-P/IF/ICC/ELISA |
Reactivity: | Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | Plin2 |
Gene ID: | 11520 |
Uniprot ID: | PLIN2_MOUSE |
Immunogen Region: | 325-425 |
Specificity: | A synthetic peptide corresponding to a sequence within amino acids 325-425 of mouse perilipin-2 (NP_031434.3). |
Immunogen Sequence: | TVLVNAQGLPQNIQDQAKHL GVMAGDIYSVFRNAASFKEV SDGVLTSSKGQLQKMKESLD EVMDYFVNNTPLNWLVGPFY PQSTEVNKASLKVQQSEVKA Q |
Tissue Specificity | Adipose tissue specific. Expressed abundantly and preferentially in fat pads. |
Post Translational Modifications | Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-230 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. |
Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. |
Protein Name | Perilipin-2 Adipophilin Adipose Differentiation-Related Protein Adrp |
Cellular Localisation | Membrane Peripheral Membrane Protein Lipid Droplet |
Alternative Antibody Names | Anti-Perilipin-2 antibody Anti-Adipophilin antibody Anti-Adipose Differentiation-Related Protein antibody Anti-Adrp antibody Anti-Plin2 antibody Anti-Adfp antibody Anti-Adrp antibody |
Information sourced from Uniprot.org