| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OLIG1 |
| Gene ID: | 116448 |
| Uniprot ID: | OLIG1_HUMAN |
| Immunogen Region: | 180-271 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-271 of human Olig1 (NP_620450.2). |
| Immunogen Sequence: | GPAAPRLLLAGLPLLAAAPG SVLLAPGAVGPPDALRPAKY LSLALDEPPCGQFALPGGGA GGPGLCTCAVCKFPHLVPAS LGLAAVQAQFSK |
| Tissue Specificity | Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable. |
| Function | Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube. |
| Protein Name | Oligodendrocyte Transcription Factor 1Oligo1Class B Basic Helix-Loop-Helix Protein 6Bhlhb6Class E Basic Helix-Loop-Helix Protein 21Bhlhe21 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Oligodendrocyte Transcription Factor 1 antibodyAnti-Oligo1 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 6 antibodyAnti-Bhlhb6 antibodyAnti-Class E Basic Helix-Loop-Helix Protein 21 antibodyAnti-Bhlhe21 antibodyAnti-OLIG1 antibodyAnti-BHLHB6 antibodyAnti-BHLHE21 antibody |
Information sourced from Uniprot.org