| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NUP42 |
| Gene ID: | 11097 |
| Uniprot ID: | NUP42_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NUPL2 (NP_031368.1). |
| Immunogen Sequence: | MAICQFFLQGRCRFGDRCWN EHPGARGAGGGRQQPQQQPS GNNRRGWNTTSQRYSNVIQP SSFSKSTPWGGSRDQEKPYF SSFDSGASTNRKEGFGLSEN PFASLSPDEQKDEKKLLEGI VKDMEVWESSGQWMFSVYSP VKKKPNISGFTDISPEELRL EYHNFLTSNNLQSYLNSVQR LINQWRNRVNELKSLNISTK |
| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | O-glycosylated. |
| Function | Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. (Microbial infection) In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. |
| Protein Name | Nucleoporin Nup42Nlp-1Nup42 HomologNucleoporin Hcg1Nucleoporin-42Nucleoporin-Like Protein 2 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-159227Reactome: R-HSA-159230Reactome: R-HSA-159231Reactome: R-HSA-159236Reactome: R-HSA-165054Reactome: R-HSA-168271Reactome: R-HSA-168276Reactome: R-HSA-168325Reactome: R-HSA-168333Reactome: R-HSA-170822Reactome: R-HSA-180746Reactome: R-HSA-180910Reactome: R-HSA-191859Reactome: R-HSA-3108214Reactome: R-HSA-3232142Reactome: R-HSA-3301854Reactome: R-HSA-3371453Reactome: R-HSA-4085377Reactome: R-HSA-4551638Reactome: R-HSA-4570464Reactome: R-HSA-4615885Reactome: R-HSA-5578749Reactome: R-HSA-5619107Reactome: R-HSA-6784531Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusNuclear Pore ComplexNucleus MembranePeripheral Membrane ProteinCytoplasmic SideExcluded From The Nucleolus |
| Alternative Antibody Names | Anti-Nucleoporin Nup42 antibodyAnti-Nlp-1 antibodyAnti-Nup42 Homolog antibodyAnti-Nucleoporin Hcg1 antibodyAnti-Nucleoporin-42 antibodyAnti-Nucleoporin-Like Protein 2 antibodyAnti-NUP42 antibodyAnti-CG1 antibodyAnti-NUPL2 antibody |
Information sourced from Uniprot.org