| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NT5C2 (382-561) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NT5C2 |
| Gene ID: |
22978 |
| Uniprot ID: |
5NTC_HUMAN |
| Immunogen Region: |
382-561 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 382-561 of human NT5C2 (NP_036361.1). |
| Immunogen Sequence: |
WTDKSSLFEELQSLDIFLAE LYKHLDSSSNERPDISSIQR RIKKVTHDMDMCYGMMGSLF RSGSRQTLFASQVMRYADLY AASFINLLYYPFSYLFRAAH VLMPHESTVEHTHVDINEME SPLATRNRTSVDFKDTDYKR HQLTRSISEIKPPNLFPLAP QEITHCHDEDDDEEEEEEEE |
| Tissue Specificity | Widely expressed. |
| Function | Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell. |
| Protein Name | Cytosolic Purine 5'-NucleotidaseCytosolic 5'-Nucleotidase IiCn-IiCytosolic Imp/Gmp-Specific 5'-NucleotidaseCytosolic Nucleoside Phosphotransferase 5'NHigh Km 5'-Nucleotidase |
| Database Links | Reactome: R-HSA-2161541Reactome: R-HSA-74259Reactome: R-HSA-9755088 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Cytosolic Purine 5'-Nucleotidase antibodyAnti-Cytosolic 5'-Nucleotidase Ii antibodyAnti-Cn-Ii antibodyAnti-Cytosolic Imp/Gmp-Specific 5'-Nucleotidase antibodyAnti-Cytosolic Nucleoside Phosphotransferase 5'N antibodyAnti-High Km 5'-Nucleotidase antibodyAnti-NT5C2 antibodyAnti-NT5B antibodyAnti-NT5CP antibodyAnti-PNT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
