| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
NRXN2 |
| Gene ID: |
9379 |
| Uniprot ID: |
NRX2A_HUMAN |
| Immunogen Region: |
1600 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1600 to the C-terminus of human NRXN2 (NP_055895.1). |
| Immunogen Sequence: |
VTSAPGFPHLPTANPTGPGE RGPPGAVEVIRESSSTTGMV VGIVAAAALCILILLYAMYK YRNRDEGSYQVDQSRNYISN SAQSNGAVVKEKAPAAPKTP SKAKKNKDKEYYV |
| Tissue Specificity | Predominantly expressed in brain. |
| Post Translational Modifications | O-glycosylated.contains heparan sulfate. Heparan sulfate attachment is required for synapse development by mediating interactions with neuroligins. |
| Function | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. |
| Protein Name | Neurexin-2Neurexin Ii-AlphaNeurexin-2-Alpha |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Presynaptic Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Neurexin-2 antibodyAnti-Neurexin Ii-Alpha antibodyAnti-Neurexin-2-Alpha antibodyAnti-NRXN2 antibodyAnti-KIAA0921 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
