| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | NRXN2 |
| Gene ID: | 9379 |
| Uniprot ID: | NRX2A_HUMAN |
| Immunogen Region: | 1600 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1600 to the C-terminus of human NRXN2 (NP_055895.1). |
| Immunogen Sequence: | VTSAPGFPHLPTANPTGPGE RGPPGAVEVIRESSSTTGMV VGIVAAAALCILILLYAMYK YRNRDEGSYQVDQSRNYISN SAQSNGAVVKEKAPAAPKTP SKAKKNKDKEYYV |
| Tissue Specificity | Predominantly expressed in brain. |
| Post Translational Modifications | O-glycosylated.contains heparan sulfate. Heparan sulfate attachment is required for synapse development by mediating interactions with neuroligins. |
| Function | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. |
| Protein Name | Neurexin-2Neurexin Ii-AlphaNeurexin-2-Alpha |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Presynaptic Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Neurexin-2 antibodyAnti-Neurexin Ii-Alpha antibodyAnti-Neurexin-2-Alpha antibodyAnti-NRXN2 antibodyAnti-KIAA0921 antibody |
Information sourced from Uniprot.org