| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NLE1 |
| Gene ID: | 54475 |
| Uniprot ID: | NLE1_HUMAN |
| Immunogen Region: | 268-353 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 268-353 of human NLE1 (NP_060566.2). |
| Immunogen Sequence: | TIKVWRAHDGVLCRTLQGHG HWVNTMALSTDYALRTGAFE PAEASVNPQDLQGSLQELKE RALSRYNLVRGQGPERLVSG SDDFTL |
| Function | Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival. |
| Protein Name | Notchless Protein Homolog 1 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Notchless Protein Homolog 1 antibodyAnti-NLE1 antibodyAnti-HUSSY-07 antibody |
Information sourced from Uniprot.org