| Tissue Specificity | Widely expressed. |
| Function | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. |
| Protein Name | Nf-Kappa-B Inhibitor-Interacting Ras-Like Protein 1I-Kappa-B-Interacting Ras-Like Protein 1Kappa B-Ras Protein 1Kappab-Ras1 |
| Database Links | Reactome: R-HSA-1810476Reactome: R-HSA-445989Reactome: R-HSA-933542 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Nf-Kappa-B Inhibitor-Interacting Ras-Like Protein 1 antibodyAnti-I-Kappa-B-Interacting Ras-Like Protein 1 antibodyAnti-Kappa B-Ras Protein 1 antibodyAnti-Kappab-Ras1 antibodyAnti-NKIRAS1 antibodyAnti-KBRAS1 antibody |
Information sourced from Uniprot.org
