| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein NipSnap homolog 2 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NIPSNAP2 |
| Gene ID: | 2631 |
| Uniprot ID: | NIPS2_HUMAN |
| Specificity: | This antibody detects endogenous levels of GBAS at Human |
| Immunogen: | Synthesized peptide derived from human GBAS |
| Function | Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria. Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2). |
| Protein Name | Protein Nipsnap Homolog 2Nipsnap2Glioblastoma-Amplified Sequence |
| Database Links | Reactome: R-HSA-9013407Reactome: R-HSA-9013409 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Protein Nipsnap Homolog 2 antibodyAnti-Nipsnap2 antibodyAnti-Glioblastoma-Amplified Sequence antibodyAnti-NIPSNAP2 antibodyAnti-GBAS antibody |
Information sourced from Uniprot.org