Host: | Mouse |
Applications: | IHC-F/IF/IP/IHC-P/WB |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-N-Cadherin is suitable for use in Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | 13A9 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | PBS with <0.1% sodium azide |
Purification: | Purified |
Concentration: | 1 mg/mL |
Storage Instruction: | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
Immunogen: | Recombinant MBP fusion protein containing the entire cytoplasmic domain of human N-cadherin |
Background | Mouse anti Human N-cadherin antibody, clone 13A9 recognizes neural cadherin, otherwise known as CD325, a calcium dependent cell-cell adhesion glycoprotein, and member of the cadherin superfamily, which links to the actin cytoskeleton via catenins, and plays a role in cell-matrix adhesion, cell growth and differentiation, and the establishment of left-right asymmetry. Mouse anti Human N-cadherin antibody, clone 13A9 does not recognize E-cadherin, M-cadherin or P-cadherin (Knudsen et al. 1995). Mouse anti Human N-cadherin antibody, clone 13A9 is a reliable marker for the differential diagnosis of pleural mesotheliomas and lung adenocarcinomas, when used in conjunction with E-cadherin (Han et al. 1997). |
Information sourced from Uniprot.org