| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4731RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:2000-1:12000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYH7 |
| Gene ID: | 4625 |
| Uniprot ID: | MYH7_HUMAN |
| Immunogen Region: | 1700-1800 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1700-1800 of human MYH7/Beta-MHC (NP_000248.2). |
| Immunogen Sequence: | KLAEQELIETSERVQLLHSQ NTSLINQKKKMDADLSQLQT EVEEAVQECRNAEEKAKKAI TDAAMMAEELKKEQDTSAHL ERMKKNMEQTIKDLQHRLDE A |
| Tissue Specificity | Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level). |
| Function | Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. |
| Protein Name | Myosin-7Myosin Heavy Chain 7Myosin Heavy Chain Slow IsoformMyhc-SlowMyosin Heavy Chain - Cardiac Muscle Beta IsoformMyhc-Beta |
| Cellular Localisation | CytoplasmMyofibrilSarcomereThick Filaments Of The Myofibrils |
| Alternative Antibody Names | Anti-Myosin-7 antibodyAnti-Myosin Heavy Chain 7 antibodyAnti-Myosin Heavy Chain Slow Isoform antibodyAnti-Myhc-Slow antibodyAnti-Myosin Heavy Chain - Cardiac Muscle Beta Isoform antibodyAnti-Myhc-Beta antibodyAnti-MYH7 antibodyAnti-MYHCB antibody |
Information sourced from Uniprot.org