• Western blot analysis of lysates from mouse lung, using MXD4 Rabbit polyclonal antibody (STJ118912) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-MXD4 antibody (110-209) (STJ118912)

SKU:
STJ118912

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MXD4 (110-209) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MXD4
Gene ID: 10608
Uniprot ID: MAD4_HUMAN
Immunogen Region: 110-209
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 110-209 of human MXD4 (NP_006445.1).
Immunogen Sequence: RRALSIKEQLQQEHRFLKRR LEQLSVQSVERVRTDSTGSA VSTDDSEQEVDIEGMEFGPG ELDSVGSSSDADDHYSLQSG TGGDSGFGPHCRRLGRPALS
Function Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Protein Name Max Dimerization Protein 4
Max Dimerizer 4
Class C Basic Helix-Loop-Helix Protein 12
Bhlhc12
Max-Associated Protein 4
Max-Interacting Transcriptional Repressor Mad4
Database Links Reactome: R-HSA-1251985
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Max Dimerization Protein 4 antibody
Anti-Max Dimerizer 4 antibody
Anti-Class C Basic Helix-Loop-Helix Protein 12 antibody
Anti-Bhlhc12 antibody
Anti-Max-Associated Protein 4 antibody
Anti-Max-Interacting Transcriptional Repressor Mad4 antibody
Anti-MXD4 antibody
Anti-BHLHC12 antibody
Anti-MAD4 antibody

Information sourced from Uniprot.org

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