| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MXD4 |
| Gene ID: | 10608 |
| Uniprot ID: | MAD4_HUMAN |
| Immunogen Region: | 110-209 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-209 of human MXD4 (NP_006445.1). |
| Immunogen Sequence: | RRALSIKEQLQQEHRFLKRR LEQLSVQSVERVRTDSTGSA VSTDDSEQEVDIEGMEFGPG ELDSVGSSSDADDHYSLQSG TGGDSGFGPHCRRLGRPALS |
| Function | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. |
| Protein Name | Max Dimerization Protein 4Max Dimerizer 4Class C Basic Helix-Loop-Helix Protein 12Bhlhc12Max-Associated Protein 4Max-Interacting Transcriptional Repressor Mad4 |
| Database Links | Reactome: R-HSA-1251985 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max Dimerization Protein 4 antibodyAnti-Max Dimerizer 4 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 12 antibodyAnti-Bhlhc12 antibodyAnti-Max-Associated Protein 4 antibodyAnti-Max-Interacting Transcriptional Repressor Mad4 antibodyAnti-MXD4 antibodyAnti-BHLHC12 antibodyAnti-MAD4 antibody |
Information sourced from Uniprot.org