| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Multiple Myeloma Oncogene 1 is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
EAU32 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Tissue culture supernatant with sodium azide |
| Concentration: |
>=263 mg/L |
| Dilution Range: |
IHC-P 1:100 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
Prokaryotic recombinant protein corresponding to 313 amino acids of the human multiple myeloma oncogene 1 (MUM-1) molecule. |
| Background | The MUM-1 (multiple myeloma oncogene 1) gene was originally identified because of its involvement in the t (6:14) translocation observed in multiple myeloma, which causes the juxtaposition of the MUM-1 gene to the Ig heavy chain locus. MUM-1 is expressed in late plasma cell directed stages of B cell differentiation and in activated T cells, suggesting that MUM-1 may serve as a marker for lympho-hemopoietic neoplasms derived from these cells. The morphologic spectrum of MUM-1 expressing cells has been found to range from that of a centrocyte to that of a plasmablast/plasma cell. Consequently the histogenic value of MUM-1 may be to provide a marker to aid in the identification of the transition from BCL-6 positive (germinal center B cells) to CD138 positive (immunoblasts and plasma cells). |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
