| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | MTPN |
| Gene ID: | 136319 |
| Uniprot ID: | MTPN_HUMAN |
| Immunogen Region: | 1-118 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human MTPN (NP_665807.1). |
| Immunogen Sequence: | MCDKEFMWALKNGDLDEVKD YVAKGEDVNRTLEGGRKPLH YAADCGQLEILEFLLLKGAD INAPDKHHITPLLSAVYEGH VSCVKLLLSKGADKTVKGPD GLTAFEATDNQAIKALLQ |
| Tissue Specificity | Ubiquitous. |
| Function | Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. |
| Protein Name | MyotrophinProtein V-1 |
| Cellular Localisation | CytoplasmNucleusPerinuclear Region |
| Alternative Antibody Names | Anti-Myotrophin antibodyAnti-Protein V-1 antibodyAnti-MTPN antibody |
Information sourced from Uniprot.org